12:00 PM

THE Homicide Squad and Professional Standards Command are investigating the death of a man outside a police station in north-west Sydney this morning. 

The man, who is believed to be in his forties but is yet to be identified, came to the station at Quakers Hill at about 10:40 am had a confrontation with a police sergeant  who then fired 'one shot' at the man.  

Emergency services were called to the scene but the man died a short time later. 

Police Assistant Commissioner Denis Clifford says a large knife was found at the scene but other details about the confrontation are unclear. 

"As I speak, we are making inquiries to locate some relatives," he told a press conference on Tuesday afternoon. 

 He says there are no indications that this incident is terrorist-related and the stand-off was very short.

"Why the man came there and why the confrontation occurred, at this stage we just don't know," he said.

"The officer who fired the shot is very distressed as you can understand.

"No police have been injured which is great."

11:18AM: A MAN is dead after a confrontation with police at a police station in Quakers Hill in north-west Sydney.

The man was shot by police during the incident, and while emergency services were called around 10:40AM, he died at the scene.

NSW Police have released a statement about the incident.

"A critical incident team from the State Crime Command's Homicide Squad will now investigate all circumstances surrounding the incident," it says.

"As per standard protocols, that investigation will be overseen by the Professional Standards Command.

"No further details are available at this time; however, no police officers have been injured.

"A brief is being prepared on behalf of the Coroner."

10:13AM: A POLICE operation is currently underway at a police station in Quakers Hill.

Police have confirmed shots have been fired.

ABC is reporting public transport and traffic is being diverted away from the area.