Wolverhampton Wanderers' Richard Stearman (centre) celebrates scoring his side's first goal in the FA Cup fourth-round match against Liverpool.
Wolverhampton Wanderers' Richard Stearman (centre) celebrates scoring his side's first goal in the FA Cup fourth-round match against Liverpool. Peter Byrne

Reds suffer embarrassing FA Cup defeat to Wolves

LIVERPOOL boss Jurgen Klopp says he is to blame for his team's shock fourth-round FA Cup exit at the hands of Championship outfit Wolverhampton Wanderers.

On a day of cup shocks, the much-changed Reds went down 2-1 at Anfield, their third loss in seven days and a second major cup defeat after going out in the EFL Cup semi-final to Southampton midweek.

Goals from Richard Stearman and Andreas Weimann did the damage for Wolves, with Divock Origi pulling back a late goal for the home team.

Klopp said he took full responsibility for the defeat, which came just days before a crucial English Premier League clash with leader Chelsea on Wednesday morning (AEST).

"No, I don't feel that they let me down or something,” the German said.

"I am responsible for the line-up. I saw them training and I thought, 'That's the line-up.'

"At the press conference on Monday we can talk about who can play and cannot play (against Chelsea) because today not a lot of the players who were not involved could play.

"I said - and it's what I mean - that I am responsible for the bad things and not just the good things, and today was obviously not good, so that's my responsibility.

"We could have played better, each boy could have played better and I know this. You always learn a little bit about (the players).”

Liverpool's defeat was not the only surprise result, with non-league Lincoln City and League One side Oxford United defeating the top two in the English Championship.

Lincoln City reached the last 16 for the first time in 115 years with a 3-1 success over Championship leader Brighton and Hove Albion at Sincil Bank, while Oxford had a 3-0 home win over Newcastle United.

There was almost another huge giant-killing act at White Hart Lane with in-form League Two side Wycombe Wanderers running Tottenham Hotspur close.

The Chairboys went into a 2-0 lead against a Spurs team missing a number of first-team regulars.

Spurs pulled a goal back through Son Heung-min and after manager Mauricio Pochettino introduced Dele Alli and Moussa Dembele, the home team levelled thanks to fellow sub Vincent Janssen's penalty.

The visitors must have thought they had won the tie after a header from Garry Thompson but had their hearts broken by a late strike from Alli before Son's second deflected goal deep into injury time spared Spurs' blushes.

There were no such problems for north London rival Arsenal, which won 5-0 at Southampton despite making 10 changes from the team that beat Burnley in the EPL last week.

Theo Walcott scored a hat-trick and Danny Welbeck hit two goals as the Gunners eased through with manager Arsene Wenger watching from the stands as he served the first match of his four-game suspension following last week's sending-off.

Chelsea cruised home against west London neighbour Brentford 4-0, while Manchester City defeated Crystal Palace 3-0 at Selhurst Park.

Middlesbrough beat Accrington Stranley 1-0, Blackburn defeated Blackpool 2-0, Burnley beat Bristol City by the same scoreline and Huddersfield Town won 4-0 at Rochdale.